Proteomic indicators of health predict Alzheimer's disease biomarker levels and dementia risk.
Heather E DarkClare PatersonGulzar N DayaZhongsheng PengMichael R DugganMurat BilgelYang AnAbhay MoghekarChristos DavatzikosSusan M ResnickKelsey LoupyMissy SimpsonJulián CandiaThomas MosleyJosef CoreshPriya PaltaLuigi FerrucciAllison ShapiroStephen A WilliamsKeenan A WalkerPublished in: Annals of neurology (2023)
Subclinical peripheral health may influence AD and neurodegenerative disease processes and relevant biomarker levels, particularly NfL. Cardiovascular health, even in the absence of clinically defined disease, plays a central role in brain aging and dementia. This article is protected by copyright. All rights reserved.