Divergent Construction of Thiochromanes and N -Arylbutanamides via Arylthiodifluoromethyl Radical-Triggered Cascade of Alkenes.

A strategy utilizing silver-catalyzed oxidative decarboxylation radical cascade cyclization of arylthiodifluoroacetic acids with alkenes for the simple and efficient preparation of difluoromethylated thiochromanes and 2,2-disubstituted- N -arylbutanamides derivatives has been developed. This approach includes good functional group tolerance, easily accessible starting materials, and operational simplicity.