Stable and durable antibody responses in SARS-recovered donors vaccinated with inactivated SARS-CoV-2 vaccine.

Tingting JiaYuankai WuGuancheng LiaoYuxuan LeiZhengyu WuFangji YangJiamin ChenQian XieChuming LuoYutian ChongHuan-le LuoYuelong Shu

Published in: Journal of medical virology (2023)

In SARS survivors, a single dose of inactivated SARS-CoV-2 vaccine provoked immune imprinting for the SARS antigen, providing protection against wild-type SARS-CoV-2 and the earlier variants of concern (VOCs) including Alpha, Beta, Gamma and Delta but not against Omicron subvariants. As such, it is important to evaluate the type and dosage of SARS-CoV-2 vaccine for SARS survivors. This article is protected by copyright. All rights reserved.

Keyphrases

sars cov
respiratory syndrome coronavirus
wild type
young adults
copy number
gene expression