Genetic associations between genes in the renin-angiotensin-aldosterone system and renal disease: a systematic review and meta-analysis.

Laura Jane SmythMarisa Cañadas-GarreRuaidhri C CappaAlexander P MaxwellAmy Jayne McKnight

Published in: BMJ open (2019)

Further biological pathway and functional analyses of the RAAS gene polymorphisms will help define how variation in components of the RAAS pathway contributes to CKD.

Keyphrases

genome wide
angiotensin ii
angiotensin converting enzyme
chronic kidney disease
dna methylation
gene expression
copy number