Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice.

Ming GuPing ZhaoShiying ZhangShengjie FanLi YangQingchun TongGuang JiShengjie Fan

Published in: British journal of pharmacology (2019)

Our data demonstrate that pharmacological activation of the FXR by BA reduces hepatocellular ER stress and attenuates NAFLD in an animal model of hepatic steatosis.

Keyphrases

endoplasmic reticulum stress
induced apoptosis
electronic health record
high fat diet induced
oxidative stress
type diabetes
machine learning
metabolic syndrome