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Generalizable Approach to Quantifying Guideline-Directed Medical Therapy.

Mirza S KhanPaul S ChanCharles F SherrodNobuhiro IkemuraAndrew J SauerPhillip G JonesGregory Y H LipJaved ButlerAdam D DeVoreLars H LundJohn A Spertus
Published in: Circulation. Heart failure (2024)
KCMO measures GDMT intensity by incorporating dosing and treatment eligibility, provides more granularity than existing methods, is easily interpretable (percentage of ideal GDMT), and can be adapted as performance measures evolve. Further study of its association with outcomes and its usefulness for quality assessment and improvement is needed.
Keyphrases
  • healthcare
  • stem cells
  • metabolic syndrome
  • mesenchymal stem cells
  • bone marrow
  • replacement therapy