Outcomes in Dutch DPP6 risk haplotype for familial idiopathic ventricular fibrillation: a focused update.
Auke T BergemanWiert F HoeksemaMartijn H van der ReeLucas V A BoersmaSing-Chien YapLisa M VerheulRutger J HassinkSaskia N van der CrabbenPaul G A VoldersChristian van der WerfArthur A M WildePieter G Postemanull nullPublished in: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation (2023)
Patients with the DPP6 risk haplotype, particularly males, are at an increased risk of IVF and sudden cardiac death. Using a risk stratification approach based on risk haplotype, sex and age, a substantial proportion of patients with a primary prevention ICD experienced appropriate ICD shocks, showing the benefit of prophylactic ICD implantation with this strategy.