Hypercoagulation detected by routine and global laboratory hemostasis assays in patients with infective endocarditis.
Ekaterina M KoltsovaMaria A SorokinaAlexandra S PisaryukNikita M PovalyaevAnastasia A IgnatovaDmitrii M PolokhovElizaveta O KotovaAlexander V BalatskiyFazoil I AtaullakhanovMikhail A PanteleevZhanna D KobalavaAnna N BalandinaPublished in: PloS one (2021)
Our findings suggest that coagulation in patients with infective endocarditis is characterized by general hypercoagulability and platelet pre-activation. Some patients, however, have hypocoagulant coagulation profile, which presumably can indicate progressing of hypercoagulation into consumption coagulopathy.