Spleen-Kidney Supplementing Formula Alleviates Renal Fibrosis in Diabetic Rats via TGF-β1-miR-21-PTEN Signaling Pathway.

Chunyu Tian Ya Wang Hong Chang Ji-An LiXiaojin La

Published in: Evidence-based complementary and alternative medicine : eCAM (2018)

SKSF could attenuate the renal damage and renal fibrosis induced in T2DM, which may be related to its regulation on the expressions of TGF-β1, PTEN, and miR-21.

Keyphrases

diabetic rats
cell proliferation
oxidative stress
pi k akt
signaling pathway
long non coding rna
transforming growth factor
long noncoding rna
epithelial mesenchymal transition
type diabetes
induced apoptosis
endothelial cells
adipose tissue
human milk
weight loss
stress induced