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Predicting susceptibility for SARS-CoV-2 infection in domestic and wildlife animals using ACE2 protein sequence homology.

Ashutosh KumarSada N PandeyVikas PareekRavi K NarayanMuneeb A FaiqChiman Kumari
Published in: Zoo biology (2020)
The article is presenting a bioinformatics based method predicting susceptibility for SARS-CoV-2 infection in domestic and wildlife animals. Recently, there were reports of cats and ferrets, dogs, minks, golden hamster, rhesus monkeys, tigers, and lions testing for SARS-CoV-2 RNA which indicated for the possible interspecies viral transmission. Our method successfully predicted the susceptibility of these animals for contracting SARS-CoV-2 infection. This method can be used as a screening tool for guiding viral RNA testing for domestic and wildlife animals at risk of getting COVID-19. We provide a list of the animals at risk of developing COVID-19 based on the susceptibility score.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • coronavirus disease
  • emergency department
  • angiotensin ii
  • small molecule
  • protein protein
  • case report
  • electronic health record
  • electron transfer