[Arterial hypertension and cognitive impairment. Neurologist's view].
A I FedinPublished in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2023)
The article presents a review of the literature on the relationship of cognitive impairment (CI) with arterial hypertension (AH). The pathogenetic mechanisms AH are characterized by the development of cerebral microangiopathy. Antihypertensive therapy (AHT) should take into account violations of autoregulation of cerebral blood flow in cerebrovascular disease and critical stenoses of large cerebral arteries, especially in fragile patients older than 80 years. The importance of AHT focused on the level of cerebral perfusion blood pressure, the severity of CI and the physical functioning of patients is emphasized. Neurocytoprotective therapy is recommended for correction of CI.
Keyphrases
- cognitive impairment
- cerebral blood flow
- arterial hypertension
- blood pressure
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- subarachnoid hemorrhage
- prognostic factors
- magnetic resonance imaging
- metabolic syndrome
- magnetic resonance
- heart rate
- brain injury
- adipose tissue
- hypertensive patients
- blood brain barrier