Effect of Nocturnal Oxygen on Blood Pressure Response to Altitude Exposure in COPD - Data from a Randomized Placebo-Controlled Cross-Over Trial.
Martina MeszarosTsogyal D LatshangSayaka S AeschbacherFabienne HuberDeborah FlueckMona LichtblauStefanie UlrichElisabeth D HaslerPhilipp M ScheiwillerLukas ReinhardStéphanie SaxerKonrad E BlochMichael FurianEsther Irene SchwarzPublished in: International journal of chronic obstructive pulmonary disease (2021)
NOT may protect from hypoxia-induced autonomic dysregulation upon altitude exposure in COPD and thus protect from a relevant increase in BP and decrease in BRS. NOT may provide cardiovascular benefits in COPD during conditions of increased hypoxemia and may be considered in COPD travelling to altitude.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- blood pressure
- study protocol
- heart rate
- clinical trial
- phase iii
- phase ii
- cystic fibrosis
- heart rate variability
- air pollution
- hypertensive patients
- metabolic syndrome
- electronic health record
- big data
- skeletal muscle
- depressive symptoms
- open label
- deep learning
- phase ii study
- locally advanced