Differential gene expression of Wharton's jelly-derived mesenchymal cells mediated by graphene oxide in basal and osteo-induced media.
Vun Vun HiewPeik Lin TeohPublished in: Molecular biology reports (2024)
GO in osteo-induced condition create a favorable microenvironment that promotes the osteogenesis of WJ-MSCs by influencing genetic and epigenetic controls. This helps in advancing our knowledge on the use of GO as priming platform and WJ-MSCs an alternate source for bone repair and regeneration.
Keyphrases
- gene expression
- stem cells
- mesenchymal stem cells
- high glucose
- dna methylation
- umbilical cord
- diabetic rats
- induced apoptosis
- healthcare
- bone marrow
- drug induced
- endothelial cells
- oxidative stress
- genome wide
- bone mineral density
- cell proliferation
- cell death
- bone regeneration
- postmenopausal women
- endoplasmic reticulum stress
- body composition
- wound healing
- pi k akt