Identification of New Markers of Angiogenic Sprouting Using Transcriptomics: New Role for RND3.

Colette A Abbey Camille L Duran Zhishi ChenYanping ChenSukanya RoyAshley Coffell Timothy M Sveeggen Sanjukta Chakraborty Gregg B Wells Jiang Chang Kayla J Bayless

Published in: Arteriosclerosis, thrombosis, and vascular biology (2024)

Validation of multiple genes, including rounding 3, revealed a functional role for this gene signature early in the angiogenic process. This study expands the list of genes associated with the acquisition of a tip cell phenotype during endothelial cell sprout initiation.

Keyphrases

single cell
genome wide
endothelial cells
bioinformatics analysis
stem cells
copy number
transcription factor