Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility.
Angela R BradburyLinda Patrick-MillerJessica LongJacquelyn PowersJill StopferAndrea FormanChristina RybakChristina RybakAmanda BrandtJacquelyn PowersWendy K ChungJane ChurpekMary B DalyLaura DigiovanniDana Farengo-ClarkDominique FetzerPamela GanschowGenerosa GranaCassandra GuldenMichael HallLynne KohlerKara MaxwellShana MerrillSusan MontgomeryRebecca MuellerSarah NielsenOlufunmilayo OlopadeKimberly RaineyChristina SeelausKatherine L NathansonSusan M DomchekPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2014)
A tiered-binned model for informed consent and genetic counseling has the potential to address the challenges of multiplex testing for cancer susceptibility and to support informed decision making and adaptive responses to testing. Future prospective studies including patient-reported outcomes are needed to inform how to best incorporate multiplex testing for cancer susceptibility into clinical practice.Genet Med 17 6, 485-492.