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Allogeneic hematopoietic cell transplantation with cord blood versus mismatched unrelated donor with post-transplant cyclophosphamide in acute myeloid leukemia.

Bhagirathbhai R DholariaMyriam LabopinJaime SanzAnnalisa RuggeriJan CornelissenHélène Labussière-WalletDidier BlaiseEdouard ForcadePatrice ChevallierAnna GrassiLudmila ZubarovskayaJürgen KuballPatrice CeballosFabio CiceriFrederic BaronBipin N SavaniArnon NaglerMohamad Mohty
Published in: Journal of hematology & oncology (2021)
CBT was associated with lower LFS, OS, and GRFS due to higher NRM, compared to MMUD allo-HCT with PTCy. In the absence of a fully matched donor, 9/10 MMUD with PTCy may be preferred over CBT.
Keyphrases
  • cord blood
  • stem cell transplantation
  • high dose
  • low dose
  • hematopoietic stem cell
  • cell proliferation
  • signaling pathway