CDK7 blockade suppresses super-enhancer-associated oncogenes in bladder cancer.

Yafei YangDonggen JiangZiyu ZhouHaiyun XiongXiangwei YangGuoyu PengWuchao XiaShang WangHanqi LeiJing ZhaoZhirong QianSong WuPang Jun

Published in: Cellular oncology (Dordrecht) (2021)

Our data indicate that exploring BC gene regulatory mechanisms associated with SEs through integrating RNA-seq and ChIP-seq data improves our understanding of BC biology and provides a basis for innovative therapies.

Keyphrases

rna seq
single cell
electronic health record
big data
high throughput
signaling pathway
cell cycle
circulating tumor cells
transcription factor
gene expression