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SMAD4: A critical regulator of cardiac neural crest cell fate and vascular smooth muscle development.

Brianna E AlexanderHuaning ZhaoSophie Astrof
Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2023)
NCs, vSMCs around the PAAs arose from a different progenitor source, rescuing AAA morphogenesis. These findings shed light on the remarkable plasticity of developmental mechanisms governing AAA development.
Keyphrases
  • smooth muscle
  • cell fate
  • epithelial mesenchymal transition
  • transcription factor
  • transforming growth factor
  • signaling pathway