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Clinical management and outcomes associated with etoposide, doxorubicin, and cisplatin plus mitotane treatment in metastatic adrenocortical carcinoma: a single institute experience.

Masaki UchiharaMaki TaniokaYuki KojimaTadaaki NishikawaKazuki SudoTatsunori ShimoiEmi NoguchiAkiko Miyagi MaeshimaKan Yonemori
Published in: International journal of clinical oncology (2021)
The EDP-M regimen had similar PFS to that observed in FIRM-ACT. Adrenal insufficiency was more frequent in the current study, but this could be managed with supportive endocrinological care such as cortisol replacement.
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