Clinical management and outcomes associated with etoposide, doxorubicin, and cisplatin plus mitotane treatment in metastatic adrenocortical carcinoma: a single institute experience.
Masaki UchiharaMaki TaniokaYuki KojimaTadaaki NishikawaKazuki SudoTatsunori ShimoiEmi NoguchiAkiko Miyagi MaeshimaKan YonemoriPublished in: International journal of clinical oncology (2021)
The EDP-M regimen had similar PFS to that observed in FIRM-ACT. Adrenal insufficiency was more frequent in the current study, but this could be managed with supportive endocrinological care such as cortisol replacement.