Endothelial progenitor cell-derived exosomes, loaded with miR-126, promoted deep vein thrombosis resolution and recanalization.

Jiacheng SunZhiwei ZhangTeng MaZiying YangJinlong ZhangXuan LiuDa LuZhenya ShenJiacheng SunQingyou Meng

Published in: Stem cell research & therapy (2018)

To sum up, our results demonstrated that EPC-derived exosomes loaded with miR-126 significantly promoted thrombus resolution in an animal model of venous thrombosis, indicating exosomes as a promising potential vehicle carrying therapeutic molecules for DVT therapy.

Keyphrases

mesenchymal stem cells
cell proliferation
long non coding rna
stem cells
drug delivery
long noncoding rna
cancer therapy
single molecule
middle cerebral artery
cell therapy
endovascular treatment