Age patterns of HSV-2 incidence and prevalence in two Ugandan communities: a catalytic incidence model applied to population-based seroprevalence data.

Lilith K WhittlesRonald M GaliwangoJosephine MpagaziAaron A R TobianRobert SsekubuguJade JacksonAustin D PeerCaitlin KennedyMargaret NakalanziAnthony NdyanaboGodfrey KigoziLarry W ChangDavid SerwaddaYukari C ManabeCharlotte A GaydosOliver LaeyendeckerThomas C QuinnSteven J ReynoldsJoseph KagaayiJeffrey W EatonM Kate Grabowski

Published in: The Journal of infectious diseases (2023)

HSV-2 prevalence and incidence were extremely high, with most infections occurring in late adolescence. Interventions against HSV-2, such as future vaccines or therapeutics, must reach young target populations. Remarkably higher HIV prevalence among HSV-2-positive individuals underscores this population as a priority for HIV prevention.

Keyphrases

risk factors
herpes simplex virus
physical activity
hepatitis c virus
antiretroviral therapy
current status
hiv positive
depressive symptoms
human immunodeficiency virus
artificial intelligence
big data
hiv testing
genetic diversity