Association of golimumab trough concentrations during maintenance with clinical, biological, endoscopic and histologic remission in patients with ulcerative colitis.
Carlos TaxoneraMaría Jesús Fernández-AceñeroDavid OlivaresMarta CalvoBegoña CasisFernando BermejoPilar López SerranoMarisa IborraFrancisco Mesonero GismeroMaia Boscá WattsMarta Maia Bosca-WattsIsabel VeraSonsoles OlivaresAlicia AlgabaCristina AlbaPublished in: Alimentary pharmacology & therapeutics (2022)
Golimumab trough concentrations during maintenance are associated with favourable treatment outcomes including endoscopic healing, histologic remission and long-term persistence on golimumab. We identified the optimal golimumab thresholds most closely associated with key outcomes.