The Impact of Nanomedicine on Soft Tissue Sarcoma Treated by Radiotherapy and/or Hyperthermia: A Review.
Maria-Eleni ZachouVassilis KoulouliasMarina ChalkiaEfstathios P EfstathopoulosKalliopi PlatoniPublished in: Cancers (2024)
This article presents a comprehensive review of nanoparticle-assisted treatment approaches for soft tissue sarcoma (STS). STS, a heterogeneous group of mesenchymal-origin tumors with aggressive behavior and low overall survival rates, necessitates the exploration of innovative therapeutic interventions. In contrast to conventional treatments like surgery, radiotherapy (RT), hyperthermia (HT), and chemotherapy, nanomedicine offers promising advancements in STS management. This review focuses on recent research in nanoparticle applications, including their role in enhancing RT and HT efficacy through improved drug delivery systems, novel radiosensitizers, and imaging agents. Reviewing the current state of nanoparticle-assisted therapies, this paper sheds light on their potential to revolutionize soft tissue sarcoma treatment and improve patient therapy outcomes.
Keyphrases
- early stage
- minimally invasive
- radiation therapy
- physical activity
- magnetic resonance imaging
- high resolution
- magnetic resonance
- radiation induced
- cancer therapy
- combination therapy
- adipose tissue
- case report
- computed tomography
- drug delivery
- photodynamic therapy
- mesenchymal stem cells
- skeletal muscle
- coronary artery bypass
- glycemic control
- fluorescence imaging