Rufinamide pretreatment attenuates ischemia-reperfusion injury in the gerbil hippocampus.

Chan Woo ParkTae-Kyeong LeeJeong Hwi ChoIn Hye KimJae-Chul LeeBich-Na ShinJi Hyeon AhnSung Koo KimMyoung Cheol ShinTaek Geun OhkJun Hwi ChoMoo-Ho WonYoung Joo LeeJeong Yeol SeoJoon Ha Park

Published in: Neurological research (2017)

These findings suggest that rufinamide can display neuroprotective effect against cerebral ischemic insults and that its neuroprotective effect may involve the attenuation of ischemia-induced glial activation.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
blood brain barrier
high glucose
neuropathic pain
diabetic rats
endothelial cells
spinal cord injury
spinal cord
stress induced