Activated autophagy restored the impaired frequency and function of regulatory T cells in chronic prostatitis.

Yi LiuYong ZhangMeng Zhang Jia-Lin MengQingqing MaZongyao HaoMeijuan ZhengLi ZhangXianguo ChenChao-Zhao Liang

Published in: The Prostate (2020)

The impaired frequency and function of Treg cells may contribute to the progression of CP/CPPS, and autophagy is a protective mechanism that promotes the differentiation of Treg cells and restores the suppressive functions of Treg cells. Autophagy may be a novel therapeutic option for patients with CP/CPPS.

Keyphrases

induced apoptosis
endoplasmic reticulum stress
regulatory t cells
cell cycle arrest
cell death
signaling pathway
oxidative stress
dendritic cells
pi k akt