Choline-An Underappreciated Component of a Mother-to-Be's Diet.
Agnieszka DymekLukasz OleksyArtur StolarczykAnna BartosiewiczPublished in: Nutrients (2024)
The nutritional status of the mother-to-be has a key impact on the proper development of the fetus. Although all nutrients are important for the developing baby, recent research indicates the importance of adequate choline intake during the periconceptional period, pregnancy, and lactation. Choline plays a key role in the biosynthesis of cell membranes, supporting liver function, neurotransmission, brain development, and DNA and histone methylation. Choline participates in the formation of a child's nervous system, supports its cognitive development, and reduces the risk of neural tube defects. The human body is incapable of producing sufficient choline to meet its needs; therefore, it must be obtained from the diet. Current data indicate that most women in their reproductive years do not achieve the recommended daily intake of choline. The presented narrative review indicates the importance of educating mothers-to-be and thereby increasing their awareness of the effects of choline on maternal and child health, which can lead to a more aware and healthy pregnancy and proper child development.
Keyphrases
- pregnancy outcomes
- physical activity
- mental health
- dna methylation
- endothelial cells
- weight loss
- preterm birth
- machine learning
- stem cells
- polycystic ovary syndrome
- multiple sclerosis
- single cell
- cell free
- electronic health record
- single molecule
- risk assessment
- skeletal muscle
- insulin resistance
- human milk
- heavy metals
- big data
- deep learning
- cell therapy
- functional connectivity
- preterm infants
- breast cancer risk