Relationship between gut microbiome Fusobacterium nucleatum and LINE-1 methylation level in esophageal cancer.

Yoshifumi BabaYoshihiro HaraTasuku ToihataKeisuke KosumiMasaaki IwatsukiShiro IwagamiYuji MiyamotoNaoya YoshidaYoshihiro KomoharaHideo Baba

Published in: Esophagus : official journal of the Japan Esophageal Society (2023)

F. nucleatum alters genome-wide methylation levels in cancer cells, which may be one of the mechanisms by which F. nucleatum affects the malignant behavior of esophageal cancer.

Keyphrases

genome wide
dna methylation
copy number
gene expression