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Understanding the pathogenesis of lean non-autoimmune diabetes in an African population with newly diagnosed diabetes.

Davis KibirigeIsaac SekitolekoWilliam LumuAngus G JonesAndrew T HattersleyLiam SmeethMoffat J Nyirenda
Published in: Diabetologia (2022)
. Diabetes in these lean individuals was more common in men, and predominantly associated with reduced pancreatic secretory function rather than insulin resistance. The underlying pathological mechanisms are unclear, but this is likely to have important management implications.
Keyphrases
  • type diabetes
  • glycemic control
  • cardiovascular disease
  • insulin resistance
  • newly diagnosed
  • adipose tissue
  • multiple sclerosis
  • metabolic syndrome
  • body composition