Neutralizing and protective murine monoclonal antibodies to the hemagglutinin of influenza H5 clades 2.3.2.1 and 2.3.4.4.
Carlotta SchueleFalko SchmeisserMegan OrrClement A MesedaAnupama VasudevanWei WangCarol D WeissAmy WoernerVajini N AtukoraleCyntia L PedroJerry P WeirPublished in: Influenza and other respiratory viruses (2023)
The results suggested that these H5 mAbs would be useful for virus and vaccine characterization. The results confirmed the functional cross-reactivity of mAb 5C2, which appears to bind a novel epitope, and suggest the therapeutic potential for H5 infections in humans with further development.