Subclinical retinal angiopathy associated with hereditary transthyretin amyloidosis - assessed with optical coherence tomography angiography.

João Heitor Marques João Coelho Jorge Malheiro Bernardete Pessoa João Melo Beirão

Published in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis (2020)

Scalloped iris in ATTRv eyes are associated with a more advanced subclinical retinal angiopathy, than eyes without scalloped iris. Our results identify for the first time and in vivo, early changes in retinal vessels in ATTRv amyloidosis. Henceforward, OCT-A may play a role in the evaluation of ATTRv patients oculopathy and the effectiveness of future eye targeting treatments.

Keyphrases

optical coherence tomography
diabetic retinopathy
optic nerve
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
multiple myeloma
prognostic factors
current status
cancer therapy