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Distinct patterns of GABAergic interneuron pathology in autism are associated with intellectual impairment and stereotypic behaviors.

Brett D DufourErin McBrideTrevor BartleyPablo JuarezVeronica Martinez-Cerdeno
Published in: Autism : the international journal of research and practice (2023)
 = 20) and assessed the relationship between the severity of symptoms and interneuron number. We found that the reduced number of inhibitory interneurons that we previously reported is linked to specific symptoms of autism spectrum disorder, particularly stereotypic movements and intellectual impairments.
Keyphrases
  • autism spectrum disorder
  • intellectual disability
  • attention deficit hyperactivity disorder
  • sleep quality