Toll-like receptor 2 stimulation augments esophageal barrier integrity.

Melanie A RuffnerLi SongKelly MaurerLihua ShiMargaret C CarrollJoshua X WangAmanda B Muir Jonathan M Spergel Kathleen E Sullivan

Published in: Allergy (2019)

Our findings implicate the TLR2 pathway as a potential regulator of esophageal epithelial barrier function and suggest that downstream chromatin modifications are associated with this effect.

Keyphrases

toll like receptor
nuclear factor
inflammatory response
transcription factor
immune response
gene expression
dna damage
genome wide
human health
risk assessment
oxidative stress
climate change