Nuclear receptor HR96 up-regulates cytochrome P450 for insecticide detoxification in Tribolium castaneum.
In-Young KimByungyoon ChoiWoo-Ram ParkYu-Ji KimBo-Eun KimSeulgi MunHueng-Sik ChoiDon-Kyu KimPublished in: Pest management science (2021)
TcHR96 plays a major role in transcriptional control of P450 enzyme for imidacloprid detoxification. Controlling TcHR96 might facilitate the regulation of insecticide tolerance in T. castaneum, thus providing a promising new strategy to manage pest beetle populations. © 2021 Society of Chemical Industry.