A novel hypoxic lncRNA, HRL-SC, promotes the proliferation and migration of human dental pulp stem cells through the PI3K/AKT signaling pathway.

Junkai ZengMing ChenYeqing YangBuling Wu

Published in: Stem cell research & therapy (2022)

Hypoxia-responsive lncRNA HRL-SC promotes the proliferation and migration of hDPSCs through the PI3K/AKT signaling pathway, and this understanding may facilitate the regenerative application of hDPSCs.

Keyphrases

stem cells
signaling pathway
endothelial cells
pi k akt
epithelial mesenchymal transition
long non coding rna
cell therapy
mesenchymal stem cells
long noncoding rna
induced apoptosis
cell proliferation
tissue engineering
endoplasmic reticulum stress