Association Between Availability of Molecular Genotyping Results and Overall Survival in Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer.
Charu AggarwalMelina E MarmarelisWei-Ting HwangDylan G ScholesTara L McWilliamsAditi P SinghLova L SunJohn KostevaMichael R CostelloRoger B CohenCorey J LangerAbigail DoucettePeter E GabrielLawrence N ShulmanKatharine A RendleJeffrey C ThompsonJustin E BekelmanErica L CarpenterPublished in: JCO precision oncology (2023)
Among patients with mNSq NSCLC in a real-world cohort, availability of molecular genotyping results before 1L therapy was associated with significantly better OS. Concurrent tissue and plasma testing was associated with a higher odds of availability of results before 1L therapy. These findings warrant renewed attention to the completion of molecular genotyping before 1L therapy.