Exploring GRHL3 polymorphisms and SNP-SNP interactions in the risk of non-syndromic oral clefts in the Brazilian population.

Camilla de Marchi Sanches AzevedoRenato Assis MachadoHercílio Martelli-JúniorSilvia Regina de Almeida ReisDarlene Camati PersuhnRicardo Della ColettaAna Lúcia Carrinho Ayroza Rangel

Published in: Oral diseases (2019)

Our results confirm the importance of GRHL3 and its interactions with previously NSOC-associated genes, including FAM49A, FOXE1, NTN1, and VAX1, in the pathogenesis of NSOC in the Brazilian population.

Keyphrases

genome wide
dna methylation
gene expression
genetic diversity
autism spectrum disorder