Difference in immunohistochemical findings among anti-PD-L1 antibodies and their relationships with CD4+ and CD8+ T cells in Japanese melanoma patients.
Daisuke YonetaJunji KatoTakafumi KamiyaKohei HorimotoSayuri SatoMasahide SawadaTomoyuki MinowaTokimasa HidaShintaro SugitaHisashi UharaPublished in: International journal of clinical oncology (2022)
The staining results by E1L3N, SP142, and 28-8 antibodies were within the allowable range, although the positive rates by E1L3N and P142 were slightly higher than that of 28-8. CD4+ TILs and CD8+ TILs were quantitatively correlated with PD-L1-positive tumor cells.