Cardiac Troponin I and Electrocardiographic Evaluation in Hospitalized Cats with Systemic Inflammatory Response Syndrome.
Michela PuglieseEttore NapoliRocky La MaestraMehmet Erman OrBengü BilgiçAnnalisa PrevitiVito BiondiAnnamaria PassantinoPublished in: Veterinary sciences (2023)
Several studies conducted on humans demonstrate the increase in cardiac troponins and the onset of arrhythmias in the course of systemic inflammatory response syndrome (SIRS). The aim of the current study was to assess the blood concentration of cardiac troponin I (cTnI) and electrocardiographic findings in SIRS-affected cats. Seventeen shorthair cats hospitalized with SIRS were enrolled (Group 1). SIRS diagnosis was performed based on the detection of at least two of the four criteria such as abnormal body temperature, abnormal heart rate (i.e., tachycardia or bradycardia), abnormal respiratory rate (i.e., tachypnea or bradypnea), and alterations of white blood cell number (i.e., leukocytes or band neutrophils). Ten cats screened for elective surgery such as neutering or dental procedures were evaluated as a control population (Group 2). They were considered healthy based on history, physical examination, hematological and biochemical profile, urinalysis, coprological exam, thyroxine assay, blood pressure measurement, and echocardiography. A physical examination, complete blood cell count, biochemistry test (including an electrolyte panel), electrocardiographic examination, and cTnI assay were carried out in each cat enrolled. Traumatic events, gastrointestinal, neoplastic, respiratory, and neurological disorders were identified as causes of SIRS in Group 1. In Group 1, a significantly higher concentration of cTnI than that in Group 2 was recorded ( p = 0.004). In 37.5% of cats with SIRS, ventricular premature complexes occurring in couplets with multiform configuration were detected. Similarly, to humans, data herein reported would indicate possible cardiac damage present in cats with SIRS diagnosis.
Keyphrases
- left ventricular
- inflammatory response
- heart rate
- blood pressure
- high throughput
- single cell
- heart rate variability
- lipopolysaccharide induced
- heart failure
- left atrial
- mental health
- physical activity
- stem cells
- spinal cord injury
- computed tomography
- oxidative stress
- case report
- lps induced
- pulmonary hypertension
- metabolic syndrome
- toll like receptor
- adipose tissue
- coronary artery bypass
- hypertensive patients
- atrial fibrillation
- artificial intelligence
- mesenchymal stem cells
- congenital heart disease
- bone marrow
- big data
- percutaneous coronary intervention
- respiratory tract
- blood glucose
- glycemic control
- sensitive detection
- clinical evaluation