H3K27M-mutant diffuse midline gliomas should be further molecularly stratified: an integrated analysis of 669 patients.

Huy Gia VuongHieu Trong LeTam N M NgoKar-Ming FungJames D BattisteRene McNall-KnappIan F Dunn

Published in: Journal of neuro-oncology (2021)

We outlined the prognostic importance of additional genetic alterations in H3-DMGs and recommended that these neoplasms should be further molecularly segregated. This may aid neuro-oncologists in appropriate risk stratification.

Keyphrases

high grade
low grade
genome wide
wild type
copy number
gene expression