Thrombolysis Outcomes in Acute Ischaemic Stroke Patients with Pre-Existing Cognitive Impairment.
Isabela V P RamnarineOmar W RasheedPeter J LaudArshad MajidKirsty A HarknessSimon M BellPublished in: Life (Basel, Switzerland) (2023)
Cognitively impaired ischaemic stroke patients experience increased morbidity, mortality, and haemorrhagic complications following thrombolytic therapy. However cognitive status is not independently predictive of most outcome measures. Further work is required to elucidate contributing factors to the poor outcomes observed in these patients and help guide thrombolysis decision-making in clinical practice.
Keyphrases
- pulmonary embolism
- acute ischemic stroke
- cognitive impairment
- clinical practice
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- liver failure
- risk factors
- prognostic factors
- stem cells
- respiratory failure
- cardiovascular disease
- patient reported outcomes
- insulin resistance
- adipose tissue
- bone marrow
- cell therapy
- acute respiratory distress syndrome