Neurological manifestations of SARS-CoV-2 - a systematic review.
Stanisław SłykIzabela DomitrzPublished in: Neurologia i neurochirurgia polska (2020)
Data regarding neurological manifestations of SARS-CoV-2 is scarce and mostly inconsistent. There are however identifiable trends which might provide a basis for future research. There is strong evidence that this novel coronavirus may be neuroinvasive and could cause a wide array of neurological symptoms and complications. Cerebrospinal fluid testing may shed more light on the occurrence of SARS-CoV-2 in the central nervous system. Clarification of the respiratory failure mechanisms requires post mortem examinations and brain tissue analysis, and further research is of the utmost importance. However, we strongly believe that the existing evidence is enough to raise awareness among clinicians and help guide them through the diagnosis and optimal therapy of COVID-19 patients.
Keyphrases
- sars cov
- cerebrospinal fluid
- respiratory failure
- respiratory syndrome coronavirus
- cerebral ischemia
- extracorporeal membrane oxygenation
- mechanical ventilation
- risk assessment
- palliative care
- high resolution
- high throughput
- big data
- stem cells
- coronavirus disease
- brain injury
- blood brain barrier
- acute respiratory distress syndrome
- bone marrow
- intensive care unit
- depressive symptoms
- functional connectivity
- smoking cessation