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NG2-positive pericytes regulate homeostatic maintenance of slow-type skeletal muscle with rapid myonuclear turnover.

Takamitsu TatsukawaKohei KanoKei-Ichi NakajimaTakashi YazawaRyoji EguchiMaki KabaraKiwamu HoriuchiTaiki HayasakaRisa MatsuoNaoyuki HasebeNobuyoshi AzumaJun-Ichi Kawabe
Published in: Stem cell research & therapy (2023)
These findings demonstrate that the turnover of myonuclei in slow-type myofibers is relatively fast, with PCs acting as myogenic stem cells-the suppliers of new myonuclei under steady conditions-and play a vital role in the homeostatic maintenance of slow-type muscles.
Keyphrases
  • skeletal muscle
  • stem cells
  • bone mineral density
  • insulin resistance
  • mesenchymal stem cells