Mismatch repair deficiency is rare in bone and soft tissue tumors.

Suk Wai Lam Marie Kostine Noel F C C de Miranda Patrick Schöffski Che-Jui LeeHans MorreauJudith V M G Bovée

Published in: Histopathology (2021)

MMR deficiency is rare in bone and soft tissue tumors. Screening focusing on tumors with myogenic differentiation, undifferentiated/unclassifiable sarcomas and in patients with a genetic predisposition / co-occurrence of other malignancies can be helpful in identifying patients potentially eligible for ICI.

Keyphrases

soft tissue
end stage renal disease
chronic kidney disease
ejection fraction
bone mineral density
newly diagnosed
peritoneal dialysis
replacement therapy
gene expression
dna methylation
bone regeneration
copy number