MRI-Targeted Prostate Biopsy Introduces Grade Inflation and Overtreatment.

Abderrahim Oussama Batouche Eugen Czeizler Timo-Pekka K Lehto Andrew M Erickson Tolou Shadbahr Teemu Daniel Laajala Joona Pohjonen Andrew Julian Vickers Tuomas K Mirtti Antti Sakari Rannikko

Published in: medRxiv : the preprint server for health sciences (2024)

GG2 cancers detected by MRI-targeted biopsy are treated more aggressively than GG1 cancers detected by systematic biopsy, despite having similar oncologic risk. To prevent further overtreatment related to the MRI pathway, treatment guidelines from the pre-MRI era need to be updated to consider changes in the diagnostic pathway.

Keyphrases

contrast enhanced
magnetic resonance imaging
diffusion weighted imaging
ultrasound guided
prostate cancer
fine needle aspiration
computed tomography
cancer therapy
drug delivery
robot assisted
newly diagnosed
benign prostatic hyperplasia
smoking cessation