Late-onset hemophagocytic lymphohistiocytosis with neurological presentation.

Sarah BenezechThierry WalzerEmily CharrierDamien HeidelbergGeneviève De Saint-BasileYves BertrandAlexandre Belot

Published in: Clinical case reports (2017)

Missense mutations in genes involved in familial hemophagocytic lymphohistiocytosis can delay the onset of this life-threatening disease. In children and adults, early recognition of aspecific features as neurological symptoms is crucial as urgent treatment is required.

Keyphrases

late onset
early onset
young adults
intellectual disability
cerebral ischemia
depressive symptoms
physical activity
smoking cessation