Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma.
Julie DevinTatiana CañequeYea-Lih LinLucie MondouletJean-Luc VeyruneMatthieu AbouladzeElvira Garcia De PacoOuissem Karmous GadachaGuillaume CartronPhilippe PaseroCaroline BretRaphaël RodriguezJérôme MoreauxPublished in: Cancer research (2022)
Iron homeostasis represents a potential therapeutic target for high-risk patients with DLBCL that can be targeted with ironomycin to induce cell death and to sensitize tumor cells to conventional treatments.