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Integrative Meta-Assembly Pipeline (IMAP): Chromosome-level genome assembler combining multiple de novo assemblies.

Giltae SongJongin LeeJuyeon KimSeokwoo KangHoyong LeeDaehong KwonDaehwan LeeGregory I LangJ Michael CherryJae Bum Kim
Published in: PloS one (2019)
We developed a cost-effective pipeline to generate chromosome-level sequence assemblies using only short-read sequencing data. Our pipeline combines the strengths of reference-guided and meta-assembly approaches. Our pipeline is available online at http://github.com/jkimlab/IMAP including a Docker image, as well as a Perl script, to help users install the IMAP package, including several prerequisite programs. Users can use IMAP to easily build the chromosome-level assembly for the genome of their interest.
Keyphrases
  • copy number
  • genome wide
  • public health
  • single cell
  • healthcare
  • big data