Multiplex Quantitative Analysis of Tumor-Infiltrating Lymphocytes and Immunotherapy Outcome in Metastatic Melanoma.

Pok Fai WongWei WeiJames W Smithy Balazs AcsMaria I TokiKim R M BlenmanDaniel ZeltermanHarriet M KlugerDavid L Rimm

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Pretreatment lymphocytic infiltration is associated with anti-PD-1 response in metastatic melanoma. Quantitative TIL analysis has potential for application in digital precision immuno-oncology as an "indicative" companion diagnostic.

Keyphrases

palliative care
peripheral blood
high resolution
risk assessment
human health
real time pcr
data analysis