Use and safety of riboflavin and UV light-treated platelet transfusions in children over a five-year period: focusing on neonates.

Riboflavin and UV light-based PRT for PLTs seems to be safe for children. Neonates required a higher number of PLT transfusions when these were PRT-treated rather than standard. A long-term follow-up for chronically transfused children and randomized clinical trials are needed.