Th2 cell differentiation from naive CD4+ T cells is enhanced by autocrine CC chemokines in atopic diseases.

Hirokuni HirataTatsuo YukawaAyae TanakaTomoyuki MiyaoTakeshi FukudaYasutsugu FukushimaKazuhiro KurasawaMasafumi Arima

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)

These data suggest that CCL17 and CCL22 produced by TSLP-primed naïve CD4+ T cells in asthma might contribute to an increase in Th2 cells via autocrine loops.

Keyphrases

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